WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

VALIDATED U.V. SPECTROPHOTOMETRIC METHOD OF SIMULTANEOUS ESTIMATION OF AMLODIPINE BESYLATE AND TELMISARTAN IN BULK AND IN TABLET DOSAGE FORM

Sandeep Singh, Marina Koland

ABSTRACT

A simple, accurate, rapid and precise simultaneous analytical method has been developed for simultaneous determination of Amlodipine Besylate and Telmisartan in bulk and in their combined tablet dosage form. Simulated gastric fluid of pH 1.2 was used as medium. Absorption Ration method was developed and is validated statistically as per ICH guidelines. The absorptions were observed at 291nm and 324nm which were selected based on overlap spectra of Amlodipine Besylate and Telmisartan. Linearity was observed by linear regression equation method for both drugs in different concentration range. The Correlation coefficient of these drugs was found to be close to 1.00, indicating good linearity. The % R.S.D. were found to be less than 2 % as required by ICH guidelines, which indicates the validity of methods. Statistical analysis proves that the method is reliable, sensitive, reproducible and selective for the simultaneous estimation of Amlodipine Besylate and Telmisartan.

Keywords: Absoption Ratio method, Amlodipine Besylate, Telmisartan, Simulated Gastric Fluid, etc.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More