WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

APOPTOSIS (PROGRAMMED CELL DEATH) - A REVIEW

Anita, H. P. Sharma, Paras Jain and Patnaik Amit

ABSTRACT

The process of apoptosis or programmed cell death is characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms. It is an intrinsic cell-suicide programme which ensures proper development by maintaining tissue homeostasis and safeguarding the organism by getting rid of damaged or infected cells that may interfere with normal function. Apoptosis is a vital component of various processes including normal cell turnover, hormone-dependent atrophy, proper development and functioning of the immune system, chemical-induced cell death and embryonic development. Dysregulation of apoptotic signalling and inappropriate apoptosis (either too little or too much) is a factor in many diseases including neurodegenerative diseases, autoimmune disorders and many types of cancer. The ability to modulate the life or death of a cell is recognized for its immense therapeutic potential. Therefore, research continues to focus on the elucidation and analysis of the cell cycle machinery and signaling pathways that control cell cycle arrest and apoptosis. The objective of this review is to provide a general overview /comprehensive information of current knowledge on the process of apoptosis including morphology, biochemistry, mechanism, regulation and the role of apoptosis in health and disease, as well as a discussion of potential alternative forms of apoptosis.

Keywords: Apoptosis, programmed cell death, intrinsic/extrinsic pathway, cancer, pathogenesis.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More