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Abstract

ANALYSIS OF PHYSICOCHEMICAL PROPERTIES AND ANTIMICROBIAL ACTIVITY OF SOME TRADITIONAL INDIAN AYURVEDIC BHASMAS

Sitansu Kumar Verma and Soni Yadav*

ABSTRACT

Traditional Medicine, ayurvedic ‘Bhasma’ formulations have been
used for treatment for thousands of years all over the world and widely
in India. These are currently being manufactured at modern plants
using modern technologies and instrumentations. They are
commercially available with modern packaging systems as well. The
area of traditional medicines yet to be developed and rationalized in
various respects like clear qualitative and quantitative information
about the medicinally active principles (inorganic/organic compounds
or conjugates etc.), pharmocodynamics, pharmacokinetics and clear
picture about mechanism(s) of action of the active principle(s) at
molecular level which involves relevant understanding of their
possible involvement in intra/extracellular signaling mechanisms. Use of sophisticated,
cutting edge analytical techniques is the need of the hour for the study and analysis of
traditional medicines. To understand the mechanism of action, the basic requirement is to
know various physicochemical properties of a given formulation. Our work is to address this
requirement and some studies were designed. Novel approaches of antimicrobial studies were
also designed for the medicine samples. In the experiments we have used commercially
available ayurvedic (SHREE Baidyanath Ayurved, Gwalior, MP, India and Divya Pharmacy,
Haridwar, Uttarakhand, India) were analyzed for various physico-chemical parameters. For
experimental purpose, Flame Photometer (Model No 128, Systronics, India), FTIR (8201 PC,
Shimadzu, Japan) were used. The application software used for FTIR analysis has been
Perkin Elmer Spectrum Version 10.03.06). For the study of possible antimicrobial activity,Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli were used. The interesting findings will help in rational development of traditional medicines.

Keywords: Escherichia coli were used. The interesting findings will help in rational development of traditional medicines


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