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Abstract

FORMULATION AND EVALUATION OF CEPHALEXIN MONOHYDRATE RECONSTITUTIONAL ORAL SUSPENSION WITH PIPERINE AND THEIR ANTIBACTERIALACTIVITY

Vijay Kumar Singh*, Vikash Kumar Mishra, Jayant Kumar Maurya, Sarvesh Kumar Singh, Ashutosh Mishra

ABSTRACT

The modern scientific and technological advancement in the pharmaceutical field had created bank of interest in reconstitutable oral suspension dosage form in the recent year. A variety of technical and scientific approaches is been conducted in the field of research and development for the formulation of reconstitutable oral suspension. By addition of piperine in reconstitutable oral suspension of cephalexin monohydrate, increase the bioavilibility of dosage form so its antibacterial activity is increase. The basic aim behind developing this reconstitutional oral suspension system was to improve the chemical stability, increase the bioavailability and controlled the duration and onset of action of the drug. The purpose of writing this thesis work on reconstitutable oral suspension of cephalexin monohydrate was to collect all the recent updates from the literature and do on this basis with the main goal to method of prepration of the reconstitution oral suspension, good qualities of ideal reconstitutional oral suspension, factors to be considerd at time of prepration and its evalution parameter.

Keywords: piperine, suspension, cephalexin.


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