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Abstract

QUANTITATIVE ESTIMATION AND VALIDATION OF URSODEOXYCHOLIC ACID TABLETS BY RP-HPLC

A.Santosh Kumar Sreevatsav*, A.K.Hareesh babu, P.Vamsi reddy, K.Radhika, Shravani Boguda, N.Mamatha.

ABSTRACT

The study involves validate analytical method for Assay of Ursodeoxycholic Acid in Udihep Tablets by HPLC as per Method of Analysis. Establish documentary evidence that the method meets the acceptance criteria, as the method given for assay is a nonpharmacoepial method and developed in-house. Here the different parameters like suitable, selective, specific, precise, linear, accurate and robust are performed for the development of analytical method of assay of Ursodeoxycholic Acid in Udihep Tablets by HPLC and obtained standard deviation and Relative standard deviation of each parameter and it found that analytical method is validated and can be used for routine analysis and for stability study.

Keywords: Ursodeoxycholic Acid, HPLC, standard deviation.


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