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Abstract

INDIAN HERBAL MEDICINES USED FOR TREATMENT OF DEMENTIA: AN OVERVIEW

Birendra Kumar, Chandraprakash Dwivedi*, Shurbhi Kesharwani, Trilochan Satapathy, Sandip Prasad Tiwari, Rajni Yadav, Kunal Chandrakar

ABSTRACT

Dementia is a progressive neurological disease of the brain. It demolishes the vital brain cells, causing trouble with memory, thinking, and behavior, brutal enough to affect work, lifelong hobbies, and social life. Recognized factors in dementia include acetylcholine deficiency, free radicals, and inflammation of the brain tissue. Since, the drugs and natural remedies have been prescribed to enhance the memory and protect the memory functioning in dementia people. The traditional herbal medicine, numerous plants have been used to treat age related cognitive disorders.The use of herbs to treat ailments would later form a large part of Ayurveda.In the first millennium BCE, there emerges in post-Vedic India the traditional medicine system known as Ayurveda, meaning the "complete knowledge for long life". According to the compendium of Charaka, the Charakasamhita health and disease are not predetermined and life may be prolonged by human effort. The compendium of Suśruta, the Suśrutasamhitā defines the purpose of medicine to cure the diseases of the sick, protect the healthy, and to prolong life. Most remarkable is Sushruta's penchant for scientific classification His medical treatise consists of 184 chapters, 1,120 conditions are listed, including injuries and illnesses relating to ageing and mental illness. Dementia is a progressive neurological disease of the brain. It demolishes the vital brain cells, causing trouble with memory, thinking, and behavior, brutal enough to affect work, lifelong hobbies, and social life. Recognized factors in dementia include acetylcholine deficiency, free radicals, and inflammation of the brain tissue, It is syndrome or set of symptoms and signs occur at the same time is due to a disease in the brain. It is progressive impairment of memory, thinking, and orientation, learning capacity, language and judgments.Dementia occur due to the cerebral ischemia, energy failure, andcalcium over load, glutamate mediated exitotoxicity, oxidative stress and structural and functional changes.

Keywords: Herbs, Dementia,Neurological,Acetyl cholinesterase,cerebral ischemia.


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