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Prerana Pujari, Ramesh V, Meena Chandran*, Chippy Regi, A R Bhat,K Krishnakumar


Hypertension is a major, worldwide health problem owing to its high prevalence and association with increased morbidity and mortality. Hypertension is a key risk factor for cardiovascular morbidity and mortality and is a leading cause of end-stage renal disease; approximately 7.1 million deaths per year can be directly attributed to poor control of blood pressure. Advances in the diagnosis and treatment of hypertension have had a major impact on management of this chronic disease. However, despite these advances, it is estimated that 1.56 billion people will suffer from hypertension by 2025. Further methods are therefore needed to reduce high blood pressure and its associated risks. The development of such treatments will be facilitated by an increased understanding of the pathogenic mechanisms underlying this condition. This review discusses the advances in our understanding of the mechanisms of hypertension and of the assessment, management and consequences of hypertension.

Keywords: Hypertension, Cardiovascular diseases, Mechanism, Treatment.

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