WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

A REVIEW ON TARDIVE DYSKINESIA AND ITS MANAGEMENT

Gamini N S Santhoshi Lakshmi*, Dr.Singuru Kiran Kumar, Kodamanchili VidyaBharghavi, Kesava Rao Kannuru, Pasam Ravi Sankar, Datla Divya Bharathi.

ABSTRACT

Tardive dyskinesia is a movement disorder and it is usually associated with the chronic use of first generation antipsychotics which includes involuntary rapid movements of face and body like grimacing, tongue movements, lip smacking, lip puckering, pursing of the lips, excessive eye blinking, rapid and involuntary movements of the limbs, torso, and phalanges. With the availability of second generation antipsychotics, the risk of tardive dyskinesia is decreased to some extent. The pathophysiology of tardive dyskinesia was not completely understood but the possible mechanisms include post-synaptic dopamine receptor hypersensitivity, striatal GABA neurons abnormality, and striatal cholinergic inter-neurons degeneration. There is no evidence based treatment which is effective in treating the tardive dyskinesia till date. Several drugs have been tried to determine their efficacy in decreasing the symptoms of tardive dyskinesia.

Keywords: Tardive dyskinesia, Dopamine, Clozapine, Vitamin E, Abnormal Involuntary Movement Scale.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More