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Rejitha Thomas M.Pharm, Ramesh. Adepu M.Pharm, PhD, B.S. Keshava MD, DM,S. Harsha MD, DM, G. Parthasarathi , M.Pharm Ph.D Juny Sebastian M.Pharm


Background: Migraine is rated as one of the leading causes of the global burden of diseases (GBD) and accounting for 1.4% of total global years lived with disability (YLD). Although migraine is not a life threatening disease however it impairs an individual‟s quality of life. Objective: To assess the influence of pharmacist provided medication counselling on knowledge, attitude and practice, medication adherence behaviour and overall health related quality of life in migraine patients. Setting: The study was conducted at outpatient Neurology clinic in a South Indian Tertiary Care Teaching Hospital. Methods: The enrolled patients were randomized into control and test groups. Validated KAP questionnaire, Morisky‟s medication adherence behaviour questionnaire and Migraine specific HRQoL questionnaire were administered to each patient at every follow up. The test group patients received education regarding the disease, medication and life style modifications. The control group patients received education at the final follow up. Results: Anxiety and stress were the major triggering factors for migraine in study patients. A statistically significant improvement (P<0.05) was observed in scores of KAP, medication adherence and migraine specific quality of life in test group patients when compared to the control group patients. Conclusion: Pharmacist provided medication and disease counselling has improved the knowledge, attitude and practice towards the disease, medication adherence behaviour, and over health related quality of life in patients with migraine.

Keywords: Migraine, Health Related Quality of life, Patient Education, Medication adherence, Therapeutic outcomes

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