WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

EFFECT OF PURE MANGIFERIN VIS-A-VIS CRUDE ETHANOLIC EXTRACT FROM MANGIFERA INDICA BARK ON HAEMATOLOGICAL PARAMETERS IN MALE ALBINO RATS

Arnab Das, Chaitali Bose, Subhasish Ghosal, Indrani Chakraborty,Nirmal Pradhan*

ABSTRACT

Different parts of mango tree have great medicinal value in different clinical fields. But the bark extract is very important in the field of pharmaceutical research and clinical applications. The present study was conducted to evaluate the effect of crude ethanolic extract (mother) of Mangifera indica bark in comparison to pure mangiferin on haematological indices in adult male albino rats. In this study, eighteen animals were divided at random into three groups i.e. vehicle control, M.indica bark extract and pure mangiferin, which received intraperitoneally 0.1ml 70% methanol, 0.1ml bark extract and 1mg pure mangiferin in 0.1ml 70% methanol/100gm b.wt./day accordingly for consecutive 14 days. Results showed no change in body growth rate, weights of heart and lung, where weights of adrenal and spleen were significantly increased in extract treated group than control. But the weights of kidney and spleen were reduced in pure mangiferin group in respect to extract treatment. Significant reduction of liver weight was observed in pure mangiferin group than control. The SGOT, SGPT and serum ALP showed no significant change. Haematological indices like Hb, TC of RBC and PCV were significantly increased in pure mangiferin group when compared to control. Notably, TC of RBC was also significantly high in pure mangiferin group when compared to extract treatment. But MCV and MCH showed significant reduction in pure mangiferin group than control and extract treatment. The MCHC showed no change. TC of WBC was significantly higher in treated groups than control. From the results, it may be concluded that mangiferin of M.indica bark extract may be an active haemopoietic principle, which can be therapeutically used for haemopoiesis.

Keywords: Mangiferin, Mangifera indica, Bark extract, RBC, WBC, Haemoglobin.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More