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Abstract

SYNTHESIS OF SOME NEW PARACETAMOL INCORPORATED SHIFF BASES AND THEIR ANTIMICROBIAL ACTIVITY

Vivek Gupta*, A. Pandurangan

ABSTRACT

Some new Schiff bases are synthesized from condensation of 4- acetamidophenoxyacetyl-Hydrazide with various aldehyde. The entire synthesized compound characterized by physical and analytical data. The chemical structures of synthesized compound were confirmed by means of IR, 1HNMR and MS. Antimicrobial activity of synthesized compounds evaluated by cup-plate method. Synthesized compound showed good antimicrobial activity.

Keywords: Antimicrobial, Paracetamol, Schiff bases.


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