WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

NATURAL GUMS AND MUCILAGES AS BIODHESIVE COMPONENTS IN ORAL CONTROLLED DRUG DELIVERY SYSTEMS: AN OVERVIEW

*Vidya Sabale1, Vandana Patel2, Archana Paranjape1

1Parul Institute of Pharmacy & Research, At and P. O. Limda, Ta. Waghodia, Dist. Vadodara-391 760, Gujarat, India.
2Babaria Institute of Pharmacy, Vadodara - Mumbai NH # 8, Varnama, Vadodara - 391 240, Gujarat, India.

ABSTRACT

Bioadhesive systems provide intimate contact between a dosage form and the absorbing tissue, which may result in high concentration in a local area and hence high drug flux through the absorbing tissue. Mucoadhesion refers to the ability of material adherence to biological tissue for an extended period of time. The efficacy of oral bioadhesive drug delivery systems is affected by the biological environment and the properties of the polymer and the drug. The lower permeability of buccal region of oral cavity compared to the sublingual site is ideal for controlled-release systems. Advantages associated with buccal drug delivery have rendered this route of administration useful for a variety of drugs. This review highlights the oral mucosa, mechanism of drug permeation, and characteristics of the desired polymers, the theories behind the adhesion of bioadhesive polymers to the mucosal epithelium. The present review also highlights the studies on natural mucilages and gums in Bioadhesive controlled drug delivery systems.

Keywords: Bioadhesion, Oral mucosa, Natural Mucilage, Gums, Polymers.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More