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Abstract

TOXICOLOGICAL STUDIES OF INDIUM (III) PORPHYRIN COMPLEXES CONTAINING SALICYLATES AS AXIAL LIGAND

Gauri D. Bajju*, Deepmala, Ved Kumar, Sujata Kundan and Altaf Ahmed

ABSTRACT

A series of Indium (III) tetraphenyl porphyrin complexes containing
substituted salicylates as axial ligands have been synthesized and
characterized by various spectroscopic techniques including UV-Vis,
IR, 1H NMR, 13C NMR and Mass. The synthesized complexes were
screened for their toxicity against bacterial strain E. coli AB 1157, a
wild-type strain, proficient to repair damage in the DNA. Except TPPIn-
4-CSA, none of the compounds showed significant MIC(minimum
inhibitory concentration) against E. coli AB 1157 which indicates that
these compounds do not exhibit any deleterious effect or toxicity to the
bacterial cell in this study.

Keywords: Salicylates; Spectroscopic techniques; toxicity; bacterial strain.


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