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Abstract

AN OVERVIEW – FREEZE DRYING PROCESS OF PARENTERAL FORMULATION

Nikhil Prabhakar Patil*, Dr. (Mrs.) Kiran Sanjay Bhise

ABSTRACT

The freeze drying technique is most suitable process for the development of unstable drug for its betterment for use as parenteral formulation by intravenous administration. The product formed by the process has proper stability period for its administration with the help of diluent for its reconstitution. The dosage conditions must be variable depending upon the requirement of patient for its administration. The product formed after lyophilization process has the proper reconstitution time, and good appearance of the cake formation. Injection form allows administration of exact dose, as the absorption is complete. Injection form also cause quick onset of action which leads to faster relief and is most useful in cases of emergency and critical treatments.

Keywords: Product type and formulation, compatibility study, finished product testing, parenteral formulation


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