WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Sonali Alkari* and Alka Chaturvedi


Introduction: Since time immemorial, A. aspera used as folk medicine, holds a reputed position as medicinal herb in different systems of medicine. The phytchemical basis of the anti-microbial and anti-inflammatory activity was evaluated using the standard guidelines issued by WHO. Aim: The effect of ethanolic extract of Achyranthes aspera was studied on Mice of either sex by using the acute mice model (Carrageenan Induced Paw Oedema). Preliminary Phyotochemical screening of A. aspera was carried out using WHO guidelines. The separation and purification of plant constituents was also carried out by using chromatographic techniques. Result: phytochemical analysis of A. aspera shown that it is rich reservoir of different types of alkaloids, steroids, triterpenoids, Cardiac Glycosides, Diterpenoids, phenolic acids, polyphenols, saponines, sapogenins & sequiterpene lactones. The results indicated that alcoholic extract of stem [35.17%] at 1 hr and leaf [28.98%] at 3 hr shows highest percentage inhibition in paw volume comparable to that of standard at 1hr. It has shown slight activity against Aspergillus niger and Verticillium moderate against Fusarium oxysporium while in-effective against Candida species It’s acetone extract has prevented the growth of Staphylococcus aureus (Gram +ve)[40mm], Escherichia coli (Gram–ve) [10mm]. Conclusion: A. aspera proven to be a rich reservoir of phytochemicals. A. aspera is an effective ant-inflammatory agent, antibacterial agent for gram positive bacteria, while it not that much effective antifungal agent. It may be due to presence of specific combination of chemicals present in this plant.

Keywords: Achyranthes aspera, diclofenac sodium, paw oedema, Carrageenan, Griseofulvin, Ciprofloxacin.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More