WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Gajanan Venkatrao Pulgamwar*, Ram S. Pentewar, Rohit U. Bharti, B. K. Sugave and Saroja P. Adepawar


Several pharmaceutical companies are currently developing bi-layer tablets, for a variety of reasons: patent extension, therapeutic, marketing to name a few. Bi-layer tablet is a new era for the successful development of controlled release formulation along with various features to provide a way of successful drug delivery system and it is suitable for sequential release of two drugs in combination, separate two incompatible substances and also for sustained release tablet in which one layer is immediate release as initial dose and second layer is maintenance dose. Bi-layer tablets can be primary option to avoid chemical incompatibilities between APIs by physical separation and to enable the development of different drug release profiles. The present article provides a review on the oral drug delivery system, types of tablets, Bilayer tablet manufacturing, various tablet presses used, quality and GMP requirements for high production output and recent developments in the field of Bilayer technology and why development and production of quality bi-layer tablets need to be carried out on purpose built tablet presses to conquer common Bilayer problems, such as layer separation, insufficient hardness, inaccurate individual layer weight control, cross contamination between the layers, reduced yield.

Keywords: Bi-layer tablet, Approaches, GMP requirement for bi-layer tablets, various tablet presses.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More