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Abstract

MEDICINAL VALUE OF SOME EDIBLE LEAFY VEGETABLES FROM BANGLADESH.

Maksuda Khatun, Shariful haque*, Md. Abul Hassan, Sheikh Nazrul Islam

ABSTRACT

The present study was aimed to evaluate the antibacterial activity and
the anti-hyperglycemic effect of fourteen edible leafy vegetables from
Bangladesh. The anti-hyperglycemic effect of fourteen edible leafy
vegetables from Bangladesh was studied on 60 healthy rabbits,
submitted weekly to subcutaneous glucose tolerance tests after gastric
administration of water, glipizide or methanol extract of leafy
vegetables. Glucose oxidase method was used to determine the serum
glucose level of normal mice. SPSS software package (version 11.5
Inc. Chicago USA.) was used to analysis the data. Among fourteen
plants tested for hypoglycemic property, ten showed significant
(p<0.05) hypoglycemic action at some point of treatment. They
lowered the serum glucose level at different rate and nearly made it normal within 28 days of
treatment, however, almost all of the nutraceuticals made the blood glucose normal by 7 day
to 14 day treatment. Seven species showed more antidiabetic properties than positive control
(Dimerol) indicating highly significant for Diabetes. These are: Chenopodium album,
Hewittia sublobata, Hygrophila auriculata, Ipomoea batatus, Malva verticillata, Piper
longum and Portulaca quadrifida. Also the methanol extract of fourteen edible leafy
vegetables were evaluated for antimicrobial activity against six gram positive and six gram
negative bacterial strains.The in-vitro antimicrobial activity was performed by agar well
diffusion method on Nutrient agar media and Muller Hinton agar media. The Methanol
extract of Leucas aspera showed moderate antimicrobial activity against only gram positive
bacteria, the methanolic extract of Enhydra fluctuans showed mild antimicrobial activity against only gram positive bacteria and the methanolic extrac of Hewittia sublobata showed very small action against only gram positive bacteria. The methanol extract of all used plants did not show any antimicrobial activity against gram negative bacteria.

Keywords: Gliclazide, Antihyperglycemic effect, Antibacterial activity, Hewittia sublobata, Enhydra fluctuans, Chenopodium album, Hewittia sublobata, Hygrophila auriculata.


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