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Abstract

SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL STUDIES OF 7-ETHYL-2, 4-BIS(4-METHOXY-PHENYL)-3-AZABICYCLO[ 3.3.1]NONAN-9-ONE

S. Mohamed Rabeek, M. Seeni Mubarak*, H.Mohamed Kasim Seit, R. Kathirvel, M. Sathyanarayanan

ABSTRACT

The newly synthesized 7-ethyl-2,4-bis(4-methoxy-phenyl)-3-azabicyclo[ 3.3.1]nonan-9-one. The compound has been derived by the condensation of 4-ethylcyclohexanone and 4-methoxybenzaldehyde using ammonium formate. The structure of the synthesized compound was elucidated by spectral studies such as IR, 1H, 13C NMR and elemental analysis. The newly synthesized compound was screened for its antimicrobial activity against staphylococcus aureus, escherichiacoli, pseudomonas aerugionosa, aspergillusnigar and mucor.

Keywords: 4-ethylcyclohexanone, 4-methoxybenzaldehyde, Spectral studies, Antimicrobial activity.


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