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Somya Gupta*, Nayyar Parvez and Pramod Kumar Sharma


The objective of the study was characterization and evaluation of Indian cherry (Cordia dichotoma) mucilage as pharmaceutical adjuvant. The mucilage was drawn out using distilled water and isolated by acetone. Various parameters such as tests for carbohydrates, protein, fat, reducing and non-reducing sugars, alkaloids, tannins, phenolic compounds, and other parameters like micromeritic properties, surface tension, swelling index and viscosity were evaluated for characterizing the extracted mucilage. The result revealed that water based extraction of mucilage has excellent flow properties. It has a good swelling index of 74.51 ± 0.503%. The gum was examined for purity by carrying out various phytochemical tests and showed that carbohydrates, alkaloids and amino acids were found to be present. The pH and surface tension of 1% solution of mucilage was found to be 8.10 ± 0.140 and 66.37 ± 0.968, respectively. The total ash value was found to be 6.23 ± 0.251 %. Extracted mucilage was insoluble in cold water and this property can be utilized for controlled drug delivery. The results of evaluated parameters showed that Cordia dichotoma mucilage has satisfactory pH and physicochemical properties, which can be used as pharmaceutical adjuvant in formulating various dosage forms.

Keywords: Cordia dichotoma, Mucilage, Adjuvant, Isolation, Characterization.

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