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Abstract

PLAUSIBLE EFFECT OF BOTTLE GOURD (LAGENARIA SICERARIA) PULP ON GLYCEMIC STATUS AND LIPID PROFILE OF THE SUBJECTS WITH TYPE II DIABETES

Shweta Sharma, Senthil Kumar, Charu Katare* and GBKS Prasad

ABSTRACT

The purpose of the study was to investigate the pulp waste obtained after juicing bottle gourd (LagenariaSiceraria) fruit belonging to cucurbitacae family, into a powdered product to be used into a dietary fibre supplement. It is reported that adequate dietary fibre is essential for proper functioning of the gut and has also been related to risk reduction for a number of chronic diseases including heart disease, certain cancers and diabetes. Therefore the study was undertaken to explore whether the pulp powder rich in fiber content exhibits any therapeutic properties when consumed by type II diabetic subjects. The study was begun with determination of acceptable dose of bottle gourd pulp powder (DBPP). Thereafter the pulp powder was administered to 25 diabetic subjects every day at fasted state for a month and baseline BMI, blood pressure of and fasting blood glucose (FBG) and serum lipids were recorded. Administration of pulp powder resulted in remarkable lowering of triglyceride and VLDL-c level (p<0.01) with a significant elevation (p<0.01) in HDL-c. A reduction in FBG and total cholesterol was also noticed though it was not statistically significant. There was significant improvement (p<0.01) in BMI of the subjects under study after a month with a decrease in systolic and diastolic blood pressure which was not statistically significant. These observations reveal that consumption of DBPP has therapeutic potential and may yield better results if consumed for longer duration.

Keywords: Lagenaria siceraria, pulp powder, diabetes, glycemic status, lipid profile.


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