WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DETECTION OF EXTENDED SPECTRUM BETA- LACTAMASE IN KLEBSIELLA PNEUMONIAE ISOLATED FROM SPUTUM IN KHARTOUM, SUDAN

Abdelhakam H Ibrahim* and Khalid A Abdelhalim

ABSTRACT

The aim of this study was to detect extended spectrum ß-lactamase (ESBL) in Klebsiella pneumoniae isolated from sputum. A total of 100 sputum specimens were collected from Alshaab Teaching Hospital during April to June 2012. Bacteriological tests of sputum specimens were performed for Klebsiella pneumoniae including inoculation on MacConkey’s agar and blood agar. The identity of the isolates was confirmed by biochemical tests. Out of 100 sputum specimens; 21 (21%) Klebsiella pneumoniae was recovered from patients with different age groups. Susceptibility test and extended spectrum ßlactamase production were carried out for each isolate. The isolates were resistance to nitrofurantoin, naldixic acid and co-trimoxazole and sensitive to imipenem. Screening tests for ESBL were performed against four types of third generation cephalosporin (3GC) and amoxyclave. Out of 21 isolates, 19 were sensitive and two were resistance. Double disc synergy test was done for the two isolates that were found resistance to the 3GC to detect ESBL and the result was positive. This study showed that Klebsiella pneumoniae considered to be one of ESBL producer.

Keywords: Klebsiella pneumonia, EBSL, 3GC, Beta-lactamase, resistance.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More