WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DEVELOPMENT OF COLORIMETRIC METHOD FOR THE ANALYSIS OF AMINOCAPROIC ACID USING DCQ

Shaza W. Shantier*, Elrasheed A. Gadkariem and Rashida Mohamed

ABSTRACT

A simple, sensitive, accurate and cost-effective colorimetric method was developed for the analysis of aminocaproic acid in bulk and injectable forms. The developed method was based on the generation of a colored complex through utilizing the known reaction of 2, 6- dichloroquinone 4-chloroimide (DCQ) with phenols, primary and secondary amines. A colored product with λmax at 680nm was formed after heating aminocaproic acid with DCQ in dimethylsulfoxide (DMSO) for 10 minutes. Stoichiometry of the reaction was studied and revealed 1:1 ratio. Beer’s law was found to be valid over the concentration range 3-15μg/ml. Regression analysis showed good correlation coefficient (not less than 0.998) with detection limit and quantification limit of 1.51μg/ml and 5.00μg/ml respectively. The mean percentage recovery was found to be 100.30 ±1.84, n=4.

Keywords: Colorimetry; Aminocaproic acid; DCQ.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More