WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

IN-SILICO SEARCH OF SOME CHEAP ANTIBIOTICS FOR TUBERCULOSIS PART-II

K.K.Srivastava*, Shubha Srivastava, Md. Tanweer Alam, Rituraj

ABSTRACT

In an attempt to search a new class of antibacterial drugs, for treatment of tuberculosis molecular docking studies with proteins 1EYN was carried out using some chromene derivatives. Some of the chromene derivatives were found to have binding energy and docking pattern very close to the originally docked molecule in 1EYN while some other show higher docking scores compared to the originally docked ligand in 1EYN protein. The quick prop results reveal that these molecules are non-toxic. The results reveal that chromenes may exhibit significant antibiotic activities against tuberculosis and indicate that this class of natural product should be considered further in the development of new and more potent antibiotics of Tuberculosis.

Keywords: docking, in-silico, 1EYN, chromene derivatives antibiotic, quick prop, druggability.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More