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Abstract

A RANDOMIZED CONTROL CLINICAL TRIAL TO EVALUATE THE EFFICACY OF BIODEGRADABLE PATCH IMPREGNATED WITH COMPOUND AYURVEDIC DRUG IN MILD TO MODERATE INFECTED WOUND

Awadhesh Kumar Pandey*, Pathak Meenakshi S. N., M. Sahu, Dr.Vijay Kumar

ABSTRACT

Objective: The present study was undertaken to assess the wound healing dermal patch as a dressing material using Compound Ayurvedic drug impregnated in a Poly(lactic acid) polymer as a biodegradable template in mild to moderate infected wounds. Material and method: Drugs were applied topically once a day in patients who were randomized into two groups; Group I was given Colloidal silver ointment, Group II was treated with Compound Ayurvedic drug impregnated in Biodegradable patch. Assessment of wound healing was based on criterias like Pain, Discharge, Slough, Surface area, Unit healing time and Histopathological study. All the above parameters were assessed on baseline, 7th day, 14th day & 21st day. Conclusion: Topical application of wound healing dermal patch (PLA-CAD) reduced pain, discharge, slough, surface area, and unit healing time of the surrounding tissue substantially in comparison to control group (MEGAHEAL).

Keywords: biodegradable patch, clinical trial, infective wound, polymer,


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