WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Nabila Morshed and Shahana Sharmin*


The aim of the present study is to determine the quality and to correlate with other different brands of pharmaceutical products marketed in Bangladesh for the healthcare of patients suffering from different respiratory inflammation like asthma, and auto-immune disorders. The experiment is done to evaluate and compare the physicochemical equivalence of different brands of Prednisolone 5mg tablet. These tablets were tested through statistical methods in accordance with the BP and USP like weight variation, thickness, hardness, friability, disintegration, in-vitro dissolution and HPLC assay. The in vitro dissolution studies of Prednisolone 5 mg tablets were carried out in pH 7 distilled water for 30 minutes using USP-II method whose absorbance were taken at 246 nm using UV spectrophotometry. Six samples showed poor in-vitro dissolution which were non-equivalent to the USP monograph specification giving Prednisolone content less than 75%. The percentage content of active ingredient of different brands were tested using HPLC assay. Samples showed values within the specifications (90-110%) except some of the companies. Two samples did not undergo disintegration at all when given in the disintegration tester. However, no major problem was found in others physical parameters like tablet weight variation, thickness, hardness and friability. Finally from the experiment we can conclude that 50% of the companies in the urban area are substandard, whereas 50% companies provide standard drugs.

Keywords: Dissolution test, Prednisolone, Quality control of tablets.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More