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Abstract

A COMPREHENSIVE BIOLOGICAL, ETHNO- PHARMACOLOGICAL and PHYTOCHEMICAL UPDATE REVIEW ON AYURVEDIC PLANT OF TERMINALIA CHEBULA (HORTOKI) OF BANGLADESH

A.K.M. Mohiuddin, Maidul Islam, Shahin Mahmud, Md. Aminul Islam Apu, Joyanta Halder, Md. Sadek Hosen Khoka, Hasibul Haque Rakib , Binita Shome and Md. Shariful Islam*

ABSTRACT

In the new era of Biotechnology, modern medicine system is so so advanced but still now, some of the common diseases are successfully and easily treated with the ayurvedic or herbal medicinal treatment; which is a major and important part of the modern treatment system. Terminalia chebula is termed the ―king of medicine‖ in the ayurvedic land of science (medicinal harbal science), due to its huge quantity of pharmacological, biological and phytochemical rich constituents. HORTOKI is the Bengali term of this plant. The demand for herbal therapeutics is now increasing in modern biological science gradually worldwide. Terminalia chebula is one of the most commonly used plants in traditional systems of medicine in Bangladesh. It is a mild, safe and effective laxative in traditional medicine. It is reported to contain various pharmacological activities including antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing, immunomodulatory, cardioprotective effect, antiaging, cytoprotective and hepatoprotective activities. It has been reported to contain various biochemical constituents including tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin and flavonoids. Several pharmacological investigations for different biological activities of Terminalia chebula in various in vivo and in vitro test models have been carried out based on the presence of biochemical ingredients and pharmacological findings. This update review gives a bird’s eye view on the biological and ethno- pharmacological properties of various phytoconstituents and the biological uses of Terminalia chebula (HORTOKI) to enrich our knowledge about this plant.

Keywords: Terminalia chebula, Pharmacological studies, Phytoconstituents, King of medicine, chebulinic acid, antimutagenic, antidiabetic.


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