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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
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Abstract

BACTERIAL PROTEINS WITH ANTI-CANDIDA PROPERTY AND THEIR MODE OF ACTION: A REVIEW.

Rajeev Meora, Vikrant Palande and Bipinraj Nirichan Kunchiraman*

ABSTRACT

Due to the undesirable effects of several anti-Candida agents and increase in development of drug resistance in Candida species, it is necessary to find new safe and effective anti-Candida agents. Natural products are best choice to screen new compounds due to various reasons. Plants and fungi are traditionally used and extensively researched for anti-Candida compounds. Many synthetic variants of these molecules are used in the market to compact many diseases. Many bacteria are reported for their ability to produce anti-Candida compounds. These compounds fall into mainly three categories, ie. Bacteriocins, biosurfactants and anti-Candida enzymes. Many of these compounds have therapeutic potential and are safe due to their specificity. Moreover, due to their diversity it is possible to find new molecules from bacterial kingdom. This review is a compilation of information on proteinaceous anti-Candida compounds from bacterial origin.

Keywords: Candidiasis, Anti-Candida proteins, Secondary metabolite, Bacteriocin and Biosurfactant.


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