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Abstract

ANTIBACTERIAL ACTIVITY OF BROWN SEAWEED PADINA TETRASTROMATICA HAUCK FROM SOUTH EAST COAST OF TAMIL NADU, INDIA.

Y.Melpha*, N. Manchu, S. Jeeva and J. Edwin James

ABSTRACT

The aim of our investigation was to evaluate the antibacterial activities of brown seaweed Padina tetrastromatica against Gram positive bacteria (Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes) and Gram negative bacteria (Pseudomonas aeruginosa, Klebsiella pneumoniae, Proteus vulgaris, Escherichia coli,). The antibacterial activity was carried out by disc diffusion method.The petroleum ether extract showed the better result than acetone, chloroform, ethanol,aqueous extracts. The strong antibacterial activity was noted in petroleum ether extracts against S. aureus (26.6±0.47 mm) and the minimum inhibition (7.6± 0.47 mm) was recorded against P. aeruginosa. P. vulgaris was found to be more resistant bacteria to the extracts of Padina tetrastromatica. Contrary to this, P. aeruginosa was susceptible to the extracts of Padina tetrastromatica. The overall antibacterial activity assessed from the above results indicates the presence of active constituents in the extracts and the seaweed can be used in pharmaceutical industry.

Keywords: Antibacterial activity, solvent extracts, disc diffusion method, Padina tetrastromatica.


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