WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

DYNAMIC DISSOLUTION AND STABILITY STUDY OF EFAVIRENZ TABLET TO CHECK THE SUITABILITY OF THE UV METHOD FOR TABLET DISSOLUTION STUDY OF THIS SINGLE COMPONENT FORMULATION.

Ajit.K.Nangare*, Abhishek.K.Shinde, Karan.K.Pawa, Amit N Chavan

ABSTRACT

Efavirenz is one of a new class of anti –viral drugs called nonnucleoside reverse transcriptase inhibitor (NNRTI). It offers the unique therapeutic prospect of treatment & management of disease and so used extensively as a single component formulation. Recently it is under clinical trials in combination with other anti-viral agents. There are no official methods reported for estimation of efavirenz. Literature survey has indicated that there are few spectrophotometric methods for its estimation in human plasma and urine. Objective of this study is to check the suitability of the UV method for tablet dissolution study of this single component formulation and also stability study of efavirenz in 0.1m HCl is studied in this study. Percentage drug release at 60 min is maximum as per the cumulative dissolution calculations.

Keywords: Efavirenz, Anti-Viral, Dissolution study, Zero order spectrum method, Stability study.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More