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Abstract

PHYTOCHEMICAL ANALYSIS AND ANTIBACTERIAL ACTIVITY OF LEAVES OF SOYMIDA FEBRIFUGA (ROXB.) A.JUSS

*Sandhya Bhoyar and Sharad Biradar

ABSTRACT

Soymida febrifuga (Roxb.) A. Juss belonging to the family Meliaceae traditionally used for the treatment of various diseases. The objectives of the present study to evaluate the antibacterial efficacy and phytochemical screening of leaves of Soymida febrifuga (Roxb.) A.Juss. The antibacterial efficacy was performed by using disc diffusion method and phytochemical screening was carried out by dilution of extract 1gm/ml respectively. The results shows that the antibacterial activity of acetone and methanol leaves extract shows maximum inhibition against pathogenic bacteria like Klebsiella pneumonae (38mm) and Pseudomonas aureginosa (37mm) at its higher concentration. The distilled water extract also shows more activity against Pseudomonas aureginosa (35mm) at 10mg/disc. The amoxicillin was used as standard drug. All the extracts show moderate activity against all the pathogenic bacteria. The preliminary phytochemical screening shows the presence of alkaloids, flavoinoids, saponins, tannins, carbohydrates, terpenoids, and amino acids. It can be concluded that the Soymida febrifuga leaves may possess excellent antibacterial property because it contains rich phytochemicals.

Keywords: Phytochemical analysis, antibacterial assay, MIC, Soymida febrifuga.


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