WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

SIMULTANEOUS ESTIMATION OF RACECADOTRIL AND OFLOXACIN IN COMBINED TABLET DOSAGE FORM

Ashish kumar S. Makadiya*, Laxman M. Prajapati, Amit K. Joshi,
Mohammed Ali L. Kharodiya

ABSTRACT

A simple, accurate, precise and specific spectrophotometric method has been developed for simultaneous determination of racecadotril and ofloxacin in its combined tablet dosage form by using methanol as a solvent. The method involves absorbance correction based on measurement of absorbance at two wavelengths at 231 nm and 323.40 nm. Method follows Beer’s linearity in the range of 10-24 μg/ml for racecadotril and 20-48 μg/ml Ofloxacin both. The mean % recoveries were found to be in the range of 99.22 – 100.66 % and 99.62 – 100.19 % for racecadotril and ofloxacin respectively. LOD and LOQ were found to be 0.1922μg/ml and 0.5826 μg/ml for racecadotril and 0.1063 μg/ml and 0.3223 μg/ml for ofloxacin respectively. Assay results of market formulation were found to be 99.24 % and 99.25 % for racecadotril and ofloxacin respectively. The proposed method has been validated as per ICH guidelines and successfully applied to the estimation of racecadotril and ofloxacin in their combined Tablet dosage form.

Keywords: Racecadotril, Ofloxacin, absorbance correction method, simultaneous, tablet.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More