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Abstract

COST ANALYSIS STUDY OF ORAL ANTI-DIABETIC DRUGS AVAILABLE IN INDIAN GOVT GENERIC (JAN AUSHADHI, JEEVANDHARA) DRUGS AND BRAND DRUGS MARKET IN RURAL / URBAN AREA OF GUNTUR, ANDHRAPRADESH, INDIA.

Nallani.Venkata Rama Rao*, Bollu Mounica Chowdary, T. Mercy Mergaret, Ramarao Nadendla.

ABSTRACT

The Indian pharmaceutical market is hub for choice of drugs to select with maximum price to minimum price under different brands and Generic Drugs .there is much variation in cost of drugs in india.there are Limited studies showing price variation in Oral Anti Diabetic Drugs. Aim & Objectives: To analyze the cost variation of oral antidiabetics of different generic drugs sold at Jan Avushadhi and jeevanadhara and Retail pharmacy available brand names of single compound and combination compounds to evaluate the difference in cost, percentage variation of cost. Methods:- Cost of single compound drugs and combination compound drugs manufactured by different companies, in the same strength, number and dosage form was obtained from Current Index of Medical Specialties” July- October 2014 and jan avushdhi, jeevandharaa drugs were compared upto February -2015. The difference in the maximum and minimum price of the same drug manufactured by different pharmaceutical companies and the percentage variation of cost was calculated. Results: In Single compound drug usage, among sulfonylurea group of drugs, Glibenclamide (2 mg) shows maximum price variation of 1980%, while Glipizide (10mg) shows variation of 55.61%. In Biguanides & Thizolidinediones groups Of drugs Metformin (1000 mg) show Maximum price variation is 125.37%, Metformin (500 mg) leat variation is 30 % and Piglitazone (30mg) show Maxmum variation 3060.97% and least variation Pioglitazoe (15 mg) is 3275 respectively. In α-glucosidases inhibitor group of drugs,Miglitol shows maximum price variation of 135.50 % and Minimum variation is 41.93 %. Meglitinides group of drugs. In this group, Rapaglinide (0.5 mg) shows Maximum price variation of 79.25 % and Minimum variation is 60 % respectively. Dipeptidyl peptidase IV inhibitors (e.g., Sitagliptin), group Sitagliptin (100 mg) shows Maximum price variation of 902.3 %. In combination therapies Glibenclamide + Metformin (5 mg+ 500 mg) combination shows the maximum variation up to 2400 % and Glipizide + Metformin (2.5mg + 250mg) showed minimum price variation of 28.60% respectively. Conclusion: This study has concluded that the cost variation increases when competition between the manufacturing companies. Government has to notice to all prescribers not write brand name , only chemical name, list essential drug list should mention all retails shops so that consumer can understand variation of cost between the manufacturing companies.. Essential drug list with cost which company providing less cost and whether these drugs are available janavushadhi or jeevandhara or generic pharmacy shops. So that we can minimize the cost burden on consumers . Wherever possible a cheaper brand should be prescribed because the superiority of any particular brand over the others has never been proved scientifically. Currently, very few medicines are under drug prices control order. Hence it is desired that the Government should bring all lifesaving and essential medicines under price control of NPPA.The average percentage price variation of different brands of the same drug is very wide and hence the physician must keep this in mind while prescribing, considering the financial background of the patient. This is necessary since the drug treatment may extend for a long time; usually lifelong.

Keywords: Price variation, Antidiabetic drugs, Branded generics, Jan avushadhi, Jeevandhara.


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