WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here

Search

Track Your Article

Abstract

IDENTIFICATION OF NOVEL TARGETS OF NEW INSULIN SENSITIZERS- STUDIES OF RELATED MECHANISM WITH OTHER GLUCOSE-LOWERING AGENTS

Mohammed H F Shalayel*, Moawia A Elbadri, Ihab Hamed Nourein, Ietimad AM Ayed, Mohammed Ayed Huneif

ABSTRACT

Aims: To explains novel targets of currently used and new insulin sensitizers with emphasis on Sodium-glucose cotransporter-2 (SGLT- 2) inhibitors, G-protein-coupled receptors (GPCRs), thiazolidinediones, insulin secretogogues, and stem cell therapy. Method: Review of recent literature that emphasizes on novel targets and techniques belonging to glucose-lowering drugs and therapeutic intervention especially those studies that focus on new insulin sensitizers. Results and conclusion: Diabetes is a global major health problem that needs challenging and renewable medications every day as we need to individualize both treatment targets and treatment strategies. Identification of novel targets and techniques for therapeutic intervention will lead to more personalized approaches to treatment and hence to define which medication to be used in whom with regard to benefits and side effects.

Keywords: Sodium-glucose cotransporter-2 (SGLT-2) inhibitors; G-protein-coupled receptors (GPCRs); Metformin; Thiazolidinediones; Glucagon-like peptide-1 (GLP-1); Peroxisome proliferator-activated receptors (PPARs).


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More