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Abstract

EFFECT OF ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF SESAMUM INDICUM

Amita S Rao1, Rashmi.Kaup.S*2, Nayanatara AK2, Kismat Anand1, Dharnappa Poojary3, Sheila R Pai2

1Dept. of Clinical Microbiology and Immunology KMC IC, Manipal University, Manipal
2Departments of Physiology, Kasturba Medical College, Bejai, Mangalore, Manipal University, Karnataka, India
3Department of Oral and Maxillofacial surgery, Manipal College of Dental Surgery, Mangalore, Manipal University, Karnataka, India

ABSTRACT

Rising prevalence of antibiotics-resistant strains of pathogenic microorganisms has been increased in the modern era. Recently, the search for substances with antimicrobial properties has gained a lot of importance, especially due to the increasing risk of infection in the ever-changing environment. The present study was aimed to determine the antimicrobial activity of sesamol against Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, and Candida albicans. The antimicrobial activity was determined using the agar well diffusion method. The diameter of the clear zone of inhibition surrounding the well was measured. The aqueous extract of Sesamol had antimicrobial activity against Bacteria and fungus. It can be concluded that Sesamol may be considered as an antibacterial and antifungal agent and can be used as a source of antibiotic substance for possible treatment of bacterial and fungal infections.

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