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Abstract

SPECTROPHOTOMETRIC DETERMINATION OF TIZANIDINE WITH 2,3 - DICHLORO-5, 6 DICYANO-1,4-BENZOQUINONE

*Dr. MALLAPU.E.RANI

Assistant Professor, Dept. of Chemistry, Rayalseema University, Kurnool, Andhra Pradesh, India.

ABSTRACT

The reaction between Tizanidine and 2,3 - dichloro 5,6-dicyaxo-1,4- benzoquinona (DDQ) in the presence of chloroform was investigated by spectrophoto metric method were proposed the determination was based on the formation of a charge transfer complex of drug solution with DDQ-Chloroform Mixture. The Orange coloured product under standardized conditions is scanned over the range 400-575mm. The calibration curve for the determination of drug, constructed by recording absorbance. Results of analysis of this method was validated statistically evaluated.

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