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Abstract

EVALUATION OF IN VITRO ANTIOXIDATIVE ACTIVITY OF STEPHANIA WIGHTII (ARN.) DUNN (MENISPERMACEAE) - AN ENDEMIC MEDICINAL PLANT

*U. Danya1, M. R.Udhayasankar2, K. Arumugasamy2, D. Punitha3 and A. Shalimol2

1PG and Research Department of Botany, Sri Parasakthi College for Women (Autonomous), Courtallam-627802, Tamil Nadu.
2 PG and Research Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore 641029, Tamil Nadu.
3Department of Botany, Providance College for Women (Autonomous),Coonoor-04, The Nilgiris. Tamil Nadu.

ABSTRACT

In this study, antioxidant activity of Stephania wightii aerial parts and tuber extracts was evaluated by total antioxidant activity, property of metal chelating and reducing power assays. The total antioxidant capacity observed in the methanolic extract of aerial parts and tuber of S. wightii was 303.23 and 312.49 nM GAE/g extract. The reducing power of aerial parts and tuber extract of S. wightii was found to be 0.55, 0.57, 0.65, 0.73, 0.93nm and 0.59, 0.62, 0.68, 0.74, 1.05nm respectively. The aerial parts and tuber extracts have exhibited maximum chelating effects of 83.49 and 92.72 mg EDTA/g. Possibly, tuber extract showed potent antioxidant activity because it contains high amount of phytoconstituents, which could react with radicals to stabilize and terminate radical chain reactions.

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