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Abstract

IN VITRO EVALUATION OF ANTHELMINTIC ACTIVITY OF EMBELIN

Prasad G. Ghugarkar*, Nupur A. Inamdar and Prof. Kailas N. Tarkase

ABSTRACT

One of the well-known herbal pharmaceutical ingredients- Embelin (Embelia ribes Burm.f.) which belongs to family (Myrsinaceae) showed significant anthelmintic results after lot many experimental trials. Thus Embelin is acting as a good anthelmintic agent. Experimental trials were carried out using Indian earthworms (Pheretima Posthuma). The various concentrations were tested for Anthelmintic activity & Albendazole is used as a standard for comparison. This is the first attempt to reveal the anthelmintic activity of embelin. The effect of Embelin against parasite was observed in very shorter time. It shows paralysis time 03 minutes 21 seconds and death time 04 minutes 07 seconds which is much superior to that of Albendazole (14.53 minutes and 23.46 minutes). By in vitro evaluation it is proved that Embelin potentiates paralysis in earthworm & ultimately it results in death of worms.

Keywords: Anthelmintic, Albendazole, Embelin, Tween 80.


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