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Abstract

ANTI-INFLAMMATORY ACTIVITY OF CARDIOSPERMUM CANESCENS WALL. (SAPINDACEAE) ON CARRAGEENAN INDUCED HIND PAW ODEMA IN RATS

*M. R. Udhayasankar1, U. Danya2, D. Punitha3, A. Shalimol, and K.Arumugasamy1

1PG and Research Department of Botany, Kongunadu Arts and Science College (Autonomous), Coimbatore 641029, Tamil Nadu.
2PG and Research Department of Botany, Sri Parasakthi College for Women (Autonomous), Courtallam-627802, Tamil Nadu.
3Department of Botany, Providence College for Women (Autonomous),Coonoor-04, The Nilgiris. Tamil Nadu.

ABSTRACT

Cardiospermum canescens is an important medicinal plant of Tamilnadu used in the traditional medicinal system allied with other species of Sapindaceae and known to possess anti-inflammatory activity. The inhibitory effect of methanolic extract of C. canescens was studied by the carrageenan induced hind paw odema in rat model. In the present study, the methanol extract of C. canescens showed the significant anti-inflammatory activity at the dose of 200mg/kg b.wt. The per cent inhibition of paw edema of C. canescens is 68.96 at the dose of 100mg/kg b.wt. and 79.11 at the dose of 200mg/kg b.wt. The results confirmed that C. canescens has potent anti-inflammatory activity.

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