WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



*Kirti Rani


Spinal muscular atrophy (SMA) is a autosomal recessive genetic neuromuscular disorder that affects the parts of nervous system in spinal cord which control the voluntary muscles movements. As it is rare neuromuscular disorders that affect as many as 1 person in 10 in the general population. This disease caused by a genetic defect in SMN1 gene which encodes SMN (Spinal muscular neuron) which is necessary for motor neurones survival. Spinal muscular atrophy is known to be most common genetic cause of infant deaths. Common symptoms are progressive deteriorating voluntary muscles activities starts form shoulders, hips, thigh and upper back and with the time, activity of muscles of lungs and oesophagus is vanished but not manifested with less recognized any kind of cognitive impairment. Even, Canada till now does not have any promising drug therapy to treat this rare debilitating disorder without any effective clinical policies. In most western countries, only palliative therapy and genetic counselling is recommended for the patients or peoples who have family history of Spinal muscular atrophy keeping its fragile X syndrome whether they can have children or must not have. Hence, governments of all countries must have all levels for effective clinical and social policies modulation to ensure that patients as well as families affected by Spinal Muscular atrophy will have access to cost effective life-saving treatments and ethical endurance program to get their maximum benefits to improve various advanced prognostic and diagnostic techniques e.g. biochemical testing; SMA gene linkage analysis; genetic counselling; PCRRFLP; quantitative SMN gene dose analysis; monosomal analysis used for the medical management of this disease. Hence, this smart study might be helpful to introduce the clinical management, effective treatments, innovative approach and ethical quandary of Spinal muscular atrophy in brief.

Keywords: Spinal muscular atrophy; SMA; SMN1; SMN2; motorneurons; neuromuscular disorder; spinal muscular neurons.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More