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Abstract

INTRA UTERINE INSEMINATION OUTCOME FOLLOWING THE DRILLING OF POLYCYSTIC OVARIAN SYNDROME OF INFERTILE WOMEN

Dr. Saad S. Al-Dujaily*, Dr. Sallama H. Al-Khdaier and Samira A. Muhsin

ABSTRACT

Background: Polycystic ovarian syndrome (PCOS) is one of world wild problem, affecting women during their reproductive age. The PCO and PCOS in Iraqi women are found as the first common cause of infertility with negative response to medical treatment .One of the second line of treatment is Laparoscopic ovarian drilling (LOD) that used to induce ovulation in women with PCOS. Objective: The objective of the present study is to investigate the effect of PCO drilling on pregnancy rate following intrauterine insemination (IUI). Patients, materials and methods: Fifty couples were involved in current study during the period from September 2013 to July 2014. Laparoscopic ovarian drilling was done for the spouses after confirming diagnosis of PCOS by laparoscopy .The women were inseminated either through intrauterine insemination or natural intercourse into two groups depending on the results of husband semen analysis. Results: There was a significant (P<0.01) decrease in LH ,testosterone and prolactin hormones with elevation in progesterone level following the LOD operation compared to before the drilling of PCOS women. The pregnancy rate following IUI was 8% and after natural intercourse was 20%.and total pregnancy rate was 14%. Conclusions: This study concluded that LOD must be recommended as line treatment option for treatment resistance of PCOS women. The drilling is effective to turn back a normal levels of reproductive hormones and ovulation with successful pregnancy . Therefore LOD considered the ultimate clinical endpoints for studies on female infertility treatment.

Keywords: Laparoscope ovarian drilling, IUI, PCOS.


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