Abstract

EVALUATION OF RENAL AND HYPOGLYCAEMIC ACTIVITIES OF ETHANOLIC EXTRACT OF ERIOBOTRYA JAPONICA FRUITS IN SWISS ALBINO MICE

Sabeeha Shafi* and Nahida Tabassum

ABSTRACT

The present study was undertaken to evaluate the phytochemical constituents, renal and hypoglycaemic effects of the ethanolic extract of the fruits of Eriobotrya japonica, commonly called as Loquat in Kashmir. The renal effects were determined by estimating the kidney function tests i.e., serum urea levels, serum creatinine levels, serum total proteins and serum albumin levels. The hypoglycaemic effects were determined by estimating blood glucose levels. The effects were compared with the normal control swiss albino mice. Histopathology of kidney was also done. The results showed significant hypoglycaemic effects and variable renal biochemical effects. The histopathology of kidney did not show any toxic signs.

Keywords: phytochemical constituents, renal and hypoglycaemic.