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Abstract

INHIBITORY EFFECT OF SOME INDIGENOUS MEDICINAL PLANTS AGAINST HUMAN PATHOGENIC BACTERIA SALMONELLA AND FUNGI CANDIDA ALBICANS: A PHENOMENOUS APPROACH

*Mohammad Danish Siddiquie, Ravi Prakash Mishra, Neha Gupta, Minakshi Joshi, Shachi Patel

Environmental Biotechnology Laboratory Department of Post Graduate Studies and Research in Biological Sciences, Rani Durgavati University. Jabalpur- 482001 (M. P.). India.

ABSTRACT

Plant based antimicrobial compounds have enormous therapeutically potential as they can serve the purpose without any side effects that are often associated with synthetic antimicrobial. Salmonella serovars is the causative agent of typhoid fever a contagious infection of the intestines that affects the whole body. Whereas Candida albicans is a diploid fungus (a form of yeast) and a causal agent of opportunistic oral and genital infections in humans. Based on the result obtained in this study, the herbal plant extracts could be much more relevant for use as antimicrobial agent. Synergistic effect experienced in combination of some plant sources for use as antimicrobial agent. The Trifala showed 10.6 mm zone of inhibition against Salmonella serovars as compared to Harro (9.6mm) whereas in case of Candida Albicans, Trifla showed (13.7mm) more zone of inhibition as compared to Harro (9.2mm). Thus, the use of this combination of plant source is recommended for use, combined usage practiced among the indigenes. Apart from combination of plant extracts like Trifala, some individual plants like Kalonji have also shown significant antimicrobial activity against Salmonella. Future research on this study can however concentrate on optimizing clinically the chemotherapeutic processes, treatment and control of these common food-borne enteric infections like typhoid in Madhya Pradesh and other parts of the country where the plants can be easily cultivated or otherwise commercialized for pharmaceutical purpose.

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