WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60


Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
Dr. Muhammad Baqir MR Fakhrildin
Download Article: Click Here


Track Your Article



Md. Reyad-ul-ferdous*, DM. Shamim Shahjahan, Md. Munirul Islam Tanvir, Shamsunnahar Sumi, Mohammad Nazmul Alam, Md. Irfan Amin Chowdury, Muhammad Moin Uddin Mazumdar, Sudipta Chowdhury, S.M.Arif Bin Alam


The aim of the present investigation was to develop oral thin films of etoricoxib, an analgesic agent and to investigate the effect of the formulation variables like concentration of film forming polymer, emulsifying agent and plasticizer on the physico chemical properties and in vitro dissolution studies. Hydroxylpropyl methylcellulose was used as a film former, Tween 80 as an emulsifying agent and polyethylene glycol (PEG) 6000 as a plasticizer. These three variables were studied at two levels thus, a 23 full factorial design was applied and six different formulations were developed by solvent casting method and evaluated. The role of HPMC in deciding the film properties was significant. It affected thickness, weight variation, folding endurance, surface PH, swelling propertics, disintegration time and in vitro dissolution rate significantly. PEG 6000 also found to play a role in deciding the properties of films. The film that contained HPMC (15 mg /film i.e. 2x3 cm2) in low levels and Tween 80 (30 mg/film i.e. 2x3 cm2) and PEG 6000 (8 mg/film i.e. 2x3 cm2) in high levels was found to be suitable for film formation with desirable physicochemical properties, faster disintegration and optimum in vitro release.

Keywords: Etoricoxib, oral films, solvent casting method, formulation variables.

[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More