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World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
            Best Paper Award :
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Abstract

GENE MUTATIONS IN APOE, Aβ, PRESINILIN GENES AND ALZHMEIRS DISEASE

Aeijaz Ul Noor*, Ruqaya Aziz, Abdul Wahid Khan, Qazi Najeeb, Ashaqullah Bhat,
Rifat Ara, Shazia Nazir

ABSTRACT

Alzheimer disease (AD) is a genetically complex disorder. Mutations
in genes ApoE, Presenilin 1 & 2 and amyloid precursor protein may
be implicated in the pathogenesis of the disease. In this review, we
discuss current advances in AD genetics, implications of the known
AD genes, on the clinical diagnosis, treatment and genetic counseling
of patients and families with early- and late-onset AD.

Keywords: Alzheimer Disease; ApoE, Presenilin 1 & 2 and Amyloid Precursor Protein.


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