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Abstract

SCREENING OF WOUND HEALING ACTIVITY ON METHANOLIC EXTRACT OF ACTINODAPHNE MADARASPATANA LEAVES BEDD

K.Yamini1*, V.Gopal2

1Research scholar, JNTUH, Hyderabad.
2Department of Pharmacognosy, Mother Theresa Post Graduate and Research Institute of Health Sciences, Pondicherry, India.

ABSTRACT

The aim of the study is to evaluate the wound healing activity of methanolic leaf extract of of Actinodaphne madaraspatana was studied respectively on two types of wound models in rats, (i) the excision and (ii) the incision wound model. The extract of Actinodaphne madaraspatana leaves produced significant response in both of the wound types tested. In the excision model the extract treated wounds were found to epithelialise faster and the rate of wound contraction was higher, as compared to control wounds. The extract facilitates the healing process as evidenced by increase in the tensile strength in the incision model. The results were also comparable to those of a standard drug Framycetin.

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