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Abstract

STUDIES ON THE EFFECT OF INFECTED CASES OF PARASITE TOXOPLASMA GONDII ON SOME SEX HORMONES

Dr. Bedir. M. AL Azawi and Farah M. Shtaib AL-Waeli

ABSTRACT

Toxoplasmosis is considered to be an epidemic disease which spreads very widely all over the world. The cause of it is the infection by the parasite Toxoplasma gondii. Its spread depends on the sociocultural and nutritional habits, climatic and geographical condition.The present study was conducted on 130 women infected with toxoplasmosis and who was suffering from abortion or without it. It was found that 90 patients who were sent by the specialist to Fatima- AL- Zahraa Hospital and Ibn- AL- Balady Hospital in Baghdad had antibodies against toxoplasmosis parasite. And 90 men infected by toxoplasmosis from National Blood Transfusion Center their ages ranged between 15- 45 years for the period from December 2014 to March 2015 Parallel to that, 60 healthy women and 30 healthy men were chosen as a control group. The results showed that the percentage of infections by the parasite for women and men were 69.23% and 66.67% respectively using ELISA and Agglutination methods. The serum concentrations of several hormones were studied such as (Estradiol, progesterone and Prolactin). The results of these trials revealed a significant (p<0.05) increase in level of Estradiol hormone in women (674.42±137.78 ng/ml) and non-significant in infected men (501.32 ± 82.09 ng/ml) and a significant (p< 0.05) decline in progesterone level in infected women (7.56 ± 1.61 ng/ml) and (5.51 ± 1.25 ng/ml) in infected men when compared with control. However, no significant differences were noticed in the level of prolactin where it registered significant decrease in infected patients in women and men comparison to control subjects.

Keywords: Toxoplasma gondi, Estradiol, progesterone and Prolactin.


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