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Abstract

A REVIEW ON ATRIGEL: A NOVEL DRUG DELIVERY SYSTEM FORMING IMPLANTS

Kiran Rajendra Bhalerao*, Harpreet Kaur Khanuja, Ismail Shaikh, Ashiwini Gaikwad, Ashish Mahajan

ABSTRACT

The administration of poorly bioavailable drug through parenteral route is regarded the most efficient for drug delivery. Parenteral delivery provides rapid onset even for the drug with narrow therapeutic window, but to maintain the systemic drug level repeated installation are required which cause the patient discomfort. Therefore, a delivery system that combines the simplicity and reliability of solid implant devices along with convenience and ease of administration of microparticles is desired. In situ gel forming systems represent a desired alternate. This article compiles the information on the in situ gel forming system i.e. ATRIGEL technology designed to provide drug release in sustained manner.

Keywords: Atrigel, Injectable in-situ forming implants, NMP.


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