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Dr. Asha M. L, *Dr. Laboni Ghorai, Dr. Basetty Neelakantam Rajarathnam, Dr. Mahesh Kumar H. M, Dr. Lekshmy J, Dr. Poulomi Dey.


The most common cause of orofacial pain is Temporomandibular Disorder (TMD), a group of medical disorders causing temporomandibular joint pain and dysfunction. The causes of TMD are varied and conventional treatment like intraoral orthoses, physical therapy, isometric exercises and dietary restrictions are often ineffective and adversely affect the quality of life. „Prolotherapy‟ is a promising approach in the management of refractory cases of TMDs where injection of therapeutic agents results in synthesis of collagen and strengthening of cartilage, thereby rejuvenating weak tendon and ligament, resolving joint laxity and patient‟s symptoms. It is a minimally invasive and maximally beneficial procedure which should be considered before long-term narcotic treatment or surgical intervention. Proper use of prolotherapy may become a safe and most effective treatment for TMD pain in future.

Keywords: Pain, Proliferant, Prolotherapy, Temporomandibular disorder.

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