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Dr. Muhammad Baqir MR Fakhrildin
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Abstract

IMPACT OF AGE AND WEIGHT ON LEVELS OF SOME REPRODUCTIVE HORMONES FOR IRAQI INFERTILE WOMEN

Prof. Dr. Muhammad-Baqir M-R. Fakhrildin and Hind Mahmood Jumaah ALMafraji*

ABSTRACT

The present study aims to assess the changes in the levels of some reproductive hormones including follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin (PRL), estradiol (E2), testosterone and thyroid stimulating hormone (TSH) classified according to age and weight for infertile women. In this study, 250 women with infertility aged 16 to 53 years were investigated who attended to the High Institute for Infertility Diagnosis and Assisted Reproductive Technologies/ Al-Nahrain University. Women were divided into four age groups: < 20 years old, 21-30 years old, 31-40 years old and > 41 years old. Blood samples were collected to determine the levels of serum FSH, LH, PRL, E2, testosterone and TSH. The crude data were statistically analyzed. Levels of S.FSH were increased gradually as the age increase. Regarding S. testosterone, highest mean level showed for female with age group (< 20 years) and lowest level of S. testosterone for females with age group (>41years). Highest levels of serum prolactin and serum testosteronewere observed for infertile women with BMI group (<18.5 kg/m2), while the lowest levels of S. PRL were assessed for women with BMI group (25-29.9 kg/m2). Regarding serum testosterone level, the lowest levels in infertile females with BMI group (18.5-24.9 and <30 kg/m2). However, the mean level of S.TSH was highest in infertile women with BMI group (18.5-24.9 kg/m2) and lowest in infertile women with BMI group (>18.5 kg/m2). From the results of present study appeared that the increasing age has a impact on the fertility of women through hormonal imbalance. Any weight abnormalities negatively affects levels of serum reproductive hormones.

Keywords: Female, Reproduction, Infertility, Hormone, Age, Weight.


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