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Abstract

SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF NOVEL HETEROCYCLIC COMPOUND

*J Sirajudeen and T. Paventhan

ABSTRACT

4-(4-chloro-6-(piperazin-1-yl)-1,3,5-triazin-2-yl) morpholine [2a] and 4-(4-chloro-6-(piperidin-1-yl)-1,3,5-triazin-2-yl) morpholine [2b] were synthesized and studied for their biological activity. These compounds were prepared by the condensation of Piperazine and Piperidine with 4-(4,6-dichloro-1,3,5-triazin-2-yl) morpholine [1] which is prepared by the reaction between 2,4,6-trichloro-1,3,5-triazine and morpholine. All the compounds were characterized by elemental analysis and spectral studies.

Keywords: 2,4,6-trichloro-1,3,5-triazine derivative, 4-(4,6- dichloro-1,3,5-triazin-2-yl) morpholine, Morpholine, Anitimicrobial activity.


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